136310-93-5 Tiotropium bromide AKSci A626
 
 
Loading Please Wait...
  A626    
Tiotropium bromide
, 99% (HPLC)
 
Spiriva
Tiova




IDENTITY
CAS Number:136310-93-5
MDL Number:MFCD00867027
MF:C19H22BrNO4S2
MW:472.42
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:217-230°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 8mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):AChR; muscarinic receptor antagonist
Form:Bromide

REVIEW

 A muscarinic receptor antagonist, often referred to as an antimuscarinic or anticholinergic agent. Although it does not display selectivity for specific muscarinic receptors, on topical application it acts mainly on M3 muscarinic receptors located on smooth muscle cells and submucosal glands leading to a reduction in smooth muscle contraction and mucus secretion, thus producing a bronchodilatory effect.

REFERENCES
[1]Karner C, Chong J, Poole P (2012). Tiotropium versus placebo for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 7:CD009285. PMID 22786525.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
None

Precautionary Statements
Notavailable


Current as of April 25, 2024


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > AChR Antagonists


PubChem