69107 Tropicamide - AK Scientific
 
 
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  Catalog ID # 69107
Tropicamide
, 98% (HPLC)
 
N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide




IDENTITY
CAS Registry #:[1508-75-4]
MDL Number:MFCD00058580
MF:C17H20N2O2
MW:284.35
EINECS:216-140-2
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:LCMS, HPLC
Physical Form:White crystalline powder
Melting Point:96-97°C
Shipping:Normal Temperature

BIOLOGICAL INFO
Application(s):Anticholinergic and a muscarinic receptor subtype M4-preferring antagonist

REVIEW

 Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle.

REFERENCES
[1]Manny RE, Hussein M, Scheiman M, Kurtz D, Niemann K, Zinzer K (July 2001). "Tropicamide (1%): an effective cycloplegic agent for myopic children". Investigative Ophthalmology & Visual Science 42 (8): 1728-35. PMID 11431435.

Risk Description(s)
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
R36/37/38:Irritating to eyes, respiratory system and skin
R42/43:May cause sensitization by inhalation and skin contact

Safety Description(s)
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



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CATEGORIES

 APIs and Bioactives > Ophthalmology, AChR Antagonists

USEFUL LINKS

  PubChem