70667 Betamethasone - AK Scientific
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  Catalog ID # 70667
, 98%

CAS Registry #:[378-44-9]
MDL Number:MFCD00062969
Physical Form:White to off-white powder
Melting Point:235-246°C
Optical Rotation:+115° - +121° (c=1, Dioxane)
Shipping:Normal Temperature


 Betamethasone is glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. Betamethasone is a glucocorticoid receptor agonist.

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[7] Kongkathip, Ngampong; Kongkathip, Boonsong; Noimai, Naratitt Synthesis of Betamethasone From the Waste of Thai Agave Sisalana Synthetic Communications (2006), 36(7), 865-874.
[8] Murphy, Kellie E.Betamethasone compared with dexamethasone for preterm birth: a call for trials Obstetrics & Gynecology (Hagerstown, MD, United States) (2007), 110(1), 7-9.
[9] Ruffatti A, Marson P, Svaluto-Moreolo G, Marozio L, Tibaldi M, Favaro M, Calligaro A, Grava C, Hoxha A, Pengo V, Punzi L.A combination therapy protocol of plasmapheresis, intravenous immunoglobulins andbetamethasone to treat anti-Ro/La-related congenital atrioventricular block. A case series andreview of the literature. Autoimmun Rev. 2013 May;12(7):768-73.
[10] Shepherd J, Taheri A, Feldman SR.Once-daily topical treatment for psoriasis: calcipotriene + betamethasone two-compound topical formulation. Clin Cosmet Investig Dermatol. 2013 Dec 19;7:19-22

Risk Description(s)
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.

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 APIs and Bioactives > Steroid Hormones