63527-52-6 Cefotaxime AKSci F941
 
 
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  F941    AKSci Bulk Reagent
Cefotaxime
, 98% (HPLC)
 



IDENTITY
CAS Number:63527-52-6
MDL Number:MFCD00864971
MF:C16H17N5O7S2
MW:455.47
EINECS:264-299-1
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:>360°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):An antibiotic with broad spectrum activity against Gram positive and Gram negative bacteria

REVIEW

 Approximately 20-36% of an intravenously administered dose of 14C-cefotaxime is excreted by the kidney as unchanged cefotaxime and 15-25% as the desacetyl derivative, the major metabolite. The desacetyl metabolite has been shown to contribute to the bactericidal activity. Two other urinary metabolites (M2 and M3) account for about 20-25%. They lack bactericidal activity.

REFERENCES
[1]Petrova, M.V., et al. 2001. Anesteziol Reanimatol. 5: 58-60. PMID: 11757305
[2] Kern, W.V., et al. 1999. N. Engl. J. Med. 341:312-318. PMID: 10423465

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
F941Cefotaxime
K035Cefotaxime sodium salt

Current as of April 19, 2024


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⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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CATEGORIES

 APIs and Bioactives > Antibacterials, Cephalosporins


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