Inhibitor of the enzyme cyclooxygenase, anti-inflammatory; analgesic; antipyretic
REVIEW Diatrizoate is an iodine-containing X-ray contrast agent. Iodated contrast agents were among the first contrast agents developed. Iodine is known to be particular electron-dense and to effectively scatter or stop X-rays. A good contrast agent requires a high density of electron-dense atoms. Therefore, the more iodine, the more dense the x-ray effect. Iodine based contrast media are water soluble and harmless to the body. These contrast agents are sold as clear colorless water solutions, the concentration is usually expressed as mg I/ml. Modern iodinated contrast agents can be used almost anywhere in the body. Most often they are used intravenously, but for various purposes they can also be used intraarterially, intrathecally (the spine) and intraabdominally - just about any body cavity or potential space.
REFERENCES
[1]
McLellan, R., et al.: Drug Metab. Dispos., 24, 1134 (1996).
[2]
Hannan, P., et al.: Antimicrob. Agents Chemother., 41, 2037 (1997).
[3]
Tasker, S., et al.: J. Microbiol. Methods., 56, 63 (2004).
[4]
Regmi, N., et al.: J. Vet. Pharmacol. Therap., 28, 553 (2005).
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