H967 Tranexamic acid - AK Scientific
 
 
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  Catalog ID # H967
Tranexamic acid
, 98%
 
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
AMCA
AMCHA
HAKU
TAMCHA




IDENTITY
CAS Registry #:[1197-18-8]
MDL Number:MFCD00001466
MF:C8H15NO2
MW:157.2102
EINECS:214-818-2
SPECIFICATIONS & PROPERTIES
Purity:98%
Available Spectra:NMR, LCMS
Physical Form:White to off-white crystalline powder or powder
Melting Point:>300°C
Shipping:Normal Temperature

REVIEW

 Tranexamic acid competitively inhibits activation of plasminogen via binding to the kringle domain, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation.

REFERENCES
[1]Wellington K, Wagstaff AJ. Tranexamic acid: a review of its use in the management of menorrhagia. Drugs. 2003;63(13):1417-33.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



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CATEGORIES

 APIs and Bioactives > Antihemorrhagics
 Amino Acids > Unnatural Amino Acids

USEFUL LINKS

  @PubChem  @Wikipedia