I745 Fenoldopam - AK Scientific
 
 
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  Catalog ID # I745
Fenoldopam
, 98% (HPLC)
 



IDENTITY
CAS Registry #:[67227-56-9]
MDL Number:MFCD00865806
MF:C16H16ClNO3
MW:305.7561
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:NMR, LCMS, HPLC
Physical Form:Yellow powder
Melting Point:210-214°C
Shipping:Normal Temperature

BIOLOGICAL INFO
Application(s):Dopamine agonist

REVIEW

 Fenoldopam is a rapid-acting vasodilator. It is an agonist for D1-like dopamine receptors and binds with moderate affinity to alpha-2-adrenoceptors. It has no significant affinity for D2-like receptors, alpha-1 and beta--adrenoceptors, 5HT1 and 5HT2 receptors, or muscarinic receptors. Fenoldopam is a racemic mixture with the R-isomer responsible for the biological activity. The R-isomer has approximately 250-fold higher affinity for D1-like receptors than does the S-isomer. In non-clinical studies, fenoldopam had no agonist effect on presynaptic D2-like dopamine receptors, or alpha- or beta- -adrenoceptors, nor did it affect angiotensin-converting enzyme activity. Fenoldopam may increase norepinephrine plasma concentration.

Risk Description(s)
R22:Harmful if swallowed.
R36:Irritating to eyes.
R42/43:May cause sensitization by inhalation and skin contact

Safety Description(s)
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.



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RELATED PRODUCTS
K106Fenoldopam methanesulfonate
I745Fenoldopam

CATEGORIES

 APIs and Bioactives > Dopamine Agonists

USEFUL LINKS

  PubChem