36791-04-5 Ribavirin AKSci J10190
 
 
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  J10190    AKSci Reference Standard
Ribavirin, >98% (HPLC), powder
 
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
Copegus
IDENTITY
CAS Number:36791-04-5
MDL Number:MFCD00058564
MF:C8H12N4O5
MW:244.20
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:171-177°C
Optical Rotation:-38° (c=1, in H2O)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 49mg/mL; H2O: 49mg/mL; EtOH: <1mg/mL
Application(s):Antimetabolite; Antiviral Agent; Viral RNA polymerase inhibitor
Form:Free Base

REVIEW
 An anti-viral drug indicated for severe RSV infection, hepatitis C infection, and other viral infections.

REFERENCES
[1]Naggie S, Osinusi A, Katsounas A, Lempicki R, Herrmann E, Thompson AJ, Clark PJ, Patel K, Muir AJ, McHutchison JG, Schlaak JF, Trippler M, Shivakumar B, Masur H, Polis MA, Kottilil S (2012). Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: impaired viral kinetics and therapeutic response. Hepatology. 56(2):444-54. PMID 22331604.
[2] Ogawa E, Furusyo N, Kajiwara E, Takahashi K, Nomura H, Tanabe Y, Satoh T, Maruyama T, Nakamuta M, Kotoh K, Azuma K, Dohmen K, Shimoda S, Hayashi J; Kyushu University Liver Disease Study [KULDS] Group (2012). Evaluation of the adverse effect of premature discontinuation of pegylated interferon a-2b and ribavirin treatment for chronic hepatitis C virus infection: results from Kyushu University Liver Disease Study. J Gastroenterol Hepatol. 27(7):1233-40. PMID 22098185.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H360

Precautionary Statements
P201; P202; P281; P308+P313; P405; P501

Current as of April 18, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
⚠️

WARNING: Attention California residents: This product can expose you to chemicals including Ribavirin, which is known to the State of California to cause birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov.




CATEGORIES
 APIs and Bioactives > Antivirals


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