132539-06-1 Olanzapine AKSci J10363
 
 
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  J10363    
Olanzapine
, 99% (HPLC), powder
 
2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine
LY-170053
Zyprexa
more..




IDENTITY
CAS Number:132539-06-1
MDL Number:MFCD00866702
MF:C17H20N4S
MW:312.43
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:189-196°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: >15mg/mL; H2O: <1mg/mL; EtOH: 9mg/mL
Application(s):5-HT2 serotonin and D1/D2 dopamine receptor antagonist
Form:Free Base

REVIEW

 An atypical antipsychotic. Olanzapine is a 5-HT2 serotonin and D1/D2 dopamine receptor antagonist.

REFERENCES
[1]Srivastava S, Wang PW, Hill SJ, Childers ME, Keller KL, Ketter TA (2012). Pilot study of the efficacy of double-blind, placebo-controlled one-week olanzapine stabilization therapy in heterogeneous symptomatic bipolar disorder patients. J Psychiatr Res. 46(7):920-6. PMID 22579071.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H413

Precautionary Statements
P264; P273; P280; P302+P352; P305+P351+P338; P321; P332+P313; P337+P313; P362; P501


Current as of April 19, 2024


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CATEGORIES

 APIs and Bioactives > Antipsychotics


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