33125-97-2 Etomidate AKSci J10465
 
 
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  J10465    AKSci Reference Standard
Etomidate
, 99% (HPLC), powder
 
Amidate




IDENTITY
CAS Number:33125-97-2
MDL Number:MFCD00869295
MF:C14H16N2O2
MW:244.29
EINECS:251-385-9
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:67-73°C
Optical Rotation:+65 ° (c=1 in EtOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 49mg/mL; H2O: <1mg/mL; EtOH: 49mg/mL
Application(s):GABAA receptors agonist
Form:Free Base

REVIEW

 A short acting intravenous anaesthetic agent used for the induction of general anaesthesia and for sedation. Etomidate is a modulator at GABAA receptors containing beta-3 subunits.

REFERENCES
[1]'Preda VA, Sen J, Karavitaki N, Grossman AB (2012). Etomidate in the management of hypercortisolaemia in Cushing''s syndrome: a review. Eur J Endocrinol. 167(2):137-43. PMID 22577107. '
[2] Trudell JR, Bertaccini E, Maciver MB (2012). Teaching an old GABA receptor new tricks. Anesth Analg. 115(2):270-3. PMID 22344244.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H410

Precautionary Statements
P264; P270; P273; P301+P312; P330; P391; P501


Current as of April 19, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Anaesthetics


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