79349-82-9 7-Amino-3-vinyl-3-cephem-4-carboxylic acid AKSci K402
 
 
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  K402    AKSci Reference Standard
7-Amino-3-vinyl-3-cephem-4-carboxylic acid
, >98%, powder
 
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-AVCA




IDENTITY
CAS Number:79349-82-9
MDL Number:MFCD07782149
MF:C9H10N2O3S
MW:226.25
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98%, powder
Physical Form (at 20°C):Solid
Melting Point:240-252°C (dec.)
Density:1.6
Refractive Index:1.69
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 An advanced beta lactam intermediate used in the preparation of the cephalosporin antibiotic cefdinir.

REFERENCES
[1]Takaya, Takao; Takasugi, Hisashi; Masugi, Takashi; Yamanaka, Hideaki; Kawabata, Kohji 7-Acylamino-3-vinylcephalosporanic acid derivatives Eur. Pat. Appl. (1981), EP 30630 A2 19810624.
[2] Kameyama, Yutaka; Yamada, Takae; Suh, Dal Soo Process for the preparation of 7-amino-3-cephem-4-carboxylic acid compounds from 7-(acylamino)-3-cephem-4-carboxylic acids PCT Int. Appl. (2000), WO 2000001703 A1 20000113.
[3] Prasad, Ashok; Prasad, Mohan Processes for the preparation of 7-amino-3-vinylcephalosporanic acid PCT Int. Appl. (2007), WO 2007013043 A2 20070201.
[4] Chao, Mingyong; Hao, Aiyou An Improved and Scaleable Preparation of 7-Amino-3-vinylcephem-4-carboxylic acid Organic Process Research & Development (2009), 13(5), 924-927.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of April 20, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Cephalosporins


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