217087-09-7 Esomeprazole magnesium trihydrate AKSci M379
 
 
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  M379    AKSci Bulk Reagent
Esomeprazole magnesium trihydrate
, 98% (HPLC)
 
(S)-Omeprazole magnesium hydrate
(T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kappaO]-1H-benzimidazolato-kappa3]-magnesium hydrate
Nexium hydrate




IDENTITY
CAS Number:217087-09-7
MDL Number:MFCD07698573
MF:C34H36MgN6O6S2.3H2O
MW:767.18
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:182-191°C
Optical Rotation:-137° - -142° (c=1, MeOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: =5 mg/mL
Application(s):Proton pump inhibitor

REVIEW

 Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

REFERENCES
[1]Lind T, Rydberg L, Kyleback A, Jonsson A, Andersson T, Hasselgren G, Holmberg J, Rohss K: Esomeprazole provides improved acid control vs. omeprazole In patients with symptoms of gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2000 Jul;14(7):861-7.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


RELATED PRODUCTS
M379Esomeprazole magnesium trihydrate
S037Omeprazole Magnesium

Current as of April 25, 2024


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CATEGORIES

 APIs and Bioactives > Proton Pump Inhibitors


PubChem