96036-02-1 Protected meropenem AKSci M858
 
 
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  M858    
Protected meropenem, 98% (HPLC)
 
4-Nitrobenzyl (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)-1-{[(4-nitrobenzyl)oxy]carbonyl}-3-pyrrolidinyl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
IDENTITY
CAS Number:96036-02-1
MDL Number:MFCD08703333
MF:C32H35N5O11S
MW:697.71
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:150-153°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 The protected meropenem is an intermediate used in the preparation of the carbopenem meropene, an beta-lactam antibiotic.

REFERENCES
[1]Sunagawa, Makoto; Matsumura, Haruki; Inoue, Takaaki; Fukasawa, Masatomo; Kato, Masahiro Carboxylic thiopyrrolidinyl beta-lactam compounds Eur. Pat. Appl. (1984), EP 126587 A1 19841128.
[2] Sunagawa, Makoto; Sasaki, Akira; Goda, Koshiro beta-Lactams Eur. Pat. Appl. (1986), EP 188816 A1 19860730.
[3] Sunagawa, Makoto; Isobe, Yutaka; Takeuchi, Yutaka; Matsumura, Haruki; Noguchi, Tetsuo; Ozaki, Yukio Preparation of a carbapenem compound in crystalline form Eur. Pat. Appl. (1988), EP 256377 A1 19880224.
[4] Sunagawa, Makoto; Matsumura, Haruki; Inoue, Takaaki; Fukasawa, Masatomo; Kato, Masuhiro A novel carbapenem antibiotic, SM-7338 structure-activity relationships Journal of Antibiotics (1990), 43(5), 519-32.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 20, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > Antibacterials, Carbapenems


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