O764 Magnesium ascorbyl phosphate - AK Scientific
 
 
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  Catalog ID # O764
Magnesium ascorbyl phosphate
, 98%
 



IDENTITY
CAS Registry #:[114040-31-2]
MDL Number:MFCD08063372
MF:C6H7O9P.Mg
MW:278.391
EINECS:281-602-2
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:Almost white powder
Melting Point:>300°C
Shipping:Normal Temperature

REVIEW

 Magnesium ascorbyl phosphate is a salt form of L-ascorbic acid or vitamin C. Unlike L-Ascorbic Acid, it does not readily degrade in formulas containing water. It is considered light-stable and oxygen-stable. It is used in cosmetics as a potent anti-oxidant, can improve appearance of aged skin. Also it is an excellent non-irritating skin whitening agent that inhibits skin cells to produce melanin, lightens age spots via tyrosinase inhibition.

REFERENCES
[1]Hwang TL, Tsai CJ, Chen JL, Changchien TT, Wang CC, Wu CM. Magnesium ascorbyl phosphate and coenzyme Q10 protect keratinocytes against UVA irradiation by suppressing glutathione depletion. Mol Med Rep. (2012) Aug;6(2): 375-8.
[2] Wang PC, Huang YL, Hou SS, Chou CH, Tsai JC. Lauroyl/palmitoyl glycol chitosan gels enhance skin delivery of magnesium ascorbyl phosphate. J Cosmet Sci. (2013) Jul-Aug;64(4): 273-86.
[3] Shaikh ZI, Mashood AA. Treatment of refractory melasma with combination of topical 5% magnesium ascorbyl phosphateand fluorescent pulsed light in Asian patients. Int J Dermatol. (2014) Jan;53(1): 93-9.
[4] Yamada, Mikio; Tamura, Hiroaki Prevention of sediment formation in magnesium ascorbate phosphate solution for pharmaceuticals, cosmetics, and beverages Jpn. Kokai Tokkyo Koho (1987), JP 62063597 A 19870320.
[5] Horiike, Shunsuke; Yamada, Arisa; Inomata, Tetsuji Stabilizer and stabilization method for ascorbic acid Jpn. Kokai Tokkyo Koho (1999), JP 11193279 A 19990721
[6] Sawaki, Shigeru; Sawaki, Shigetoyo Skin preparation for external use/Skin preparation comprising hydrolysate of rice bran extract and whitening agent for external use capable of preventing and treating skin pigmentaion Jpn. Kokai Tokkyo Koho (2000), JP 2000044459 A 20000215
[7] Elmore AR.Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, MagnesiumAscorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium AscorbylPhosphate as used in cosmetics. Int J Toxicol. 2005;24 Suppl 2:51-111

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


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CATEGORIES

 APIs and Bioactives > Vitamins

USEFUL LINKS

  PubChem