P002 Diammonium glycyrrhizinate - AK Scientific
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  Catalog ID # P002
Diammonium glycyrrhizinate
, 98%

CAS Registry #:[79165-06-3]
MDL Number:MFCD08460395
Physical Form:White to off-white crystalline powder
Shipping:Normal Temperature

Application(s):Anti-Inflammatory Agent


 Diammonium glycyrrhizinate is a salt of glycyrrhetinic acid, a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties. It has some additional pharmacological properties including antiviral, antifungal, antiprotozoal, and antibacterial activities.

[1]Li, Quanzhi; Duan, Jingli. Systematic review of diammonium glycyrrhizinate in the treatment of drug-induced liver injury. Zhongguo Yaofang. (2010) 21(12): 1100-1105.
[2] Ming, Lee Jia; Yin, Adeline Chia Yoke. Therapeutic effects of glycyrrhizic acid. Natural Product Communications. (2013) 8(3): 415-418.
[3] Harwansh, R. K.; Patra, K. C.; Pareta, S. K.; Singh, J.; Biswas, R. Pharmacological studies on Glycyrrhiza glabra: a review. Pharmacologyonline. (2011) (2, Newsletters): 1032-1038.
[4] Zhou, Jingliang; Zhang, Xiaoliang Method for preparing glycyrrhizic acid diammonium salt Faming Zhuanli Shenqing Gongkai Shuomingshu (2006), CN 1743338 A 20060308.
[5] Chu, Jiegen; Shen, Cimin Heterogeneous reaction for preparing 18alpha-glycyrrhizic acid and its salt Faming Zhuanli Shenqing Gongkai Shuomingshu (2006), CN 1752096 A 20060329
[6] Hayashi, Hiroaki; Sudo, Hiroshi Economic importance of licorice Plant Biotechnology (Tokyo, Japan) (2009), 26(1), 101-104.
[7] Shamsa, F.; Ohtsuki, K.; Hasanzadeh, E.; Rezazadeh, Sh.The anti-inflammatory and anti-viral effects of an ethnic medicine: glycyrrhizin Faslnamah-i Giyahan-i Daruyi (2010), 9(Suppl. 6), 1-28.
[8] Zhang, Ming-fa; Jin, Yu-jie; Shen, Ya-qin Advances in pharmacological study on encephalic injury protection and memory improvement of glycyrrhizic acid Yaowu Pingjia Yanjiu (2013), 36(1), 59-63.
[9] Kao, Tzu-Chien; Wu, Chi-Hao; Yen, Gow-Chin Bioactivity and Potential Health Benefits of Licorice Journal of Agricultural and Food Chemistry (2014), 62(3), 542-553.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.

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