P087 Agmatine sulfate - AK Scientific
 
 
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  Catalog ID # P087
Agmatine sulfate
, 98%
 
1-Amino-4-guanidinobutane sulfate salt
4-Guanidinobutylamine sulfate salt
N-(4-Aminobutyl)guanidine sulfate salt




IDENTITY
CAS Registry #:[2482-00-0]
MDL Number:MFCD00013109
MF:C5H16N4O4S
MW:228.27
EINECS:219-617-3
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:White to off-white powder
Melting Point:234-238°C
Shipping:Normal Temperature

BIOLOGICAL INFO
Solubility:H2O: 50mg/mL; EtOH: insoluble
Application(s):Nitric oxide synthase (NOS) inhibitor; NMDA-activated ion channels blocker
Form:Sulfate salt

REVIEW

 Agmatine sulfate is a natural metabolite salt of the amino acid arginine. It is formed when arginine is decarboxylated by the enzyme arginine decarboxylase and is found naturally. Some of the biochemical mechanisms discovered so far concern agmatine's indication for diabetes, neuroprotection, and psychiatric conditions.

REFERENCES
[1]Su, Rui-Bin; Wang, Wei-Ping; Lu, Xin-Qiang; Wu, Ning; Liu, Zhi-Min; Li, Jin. Agmatine blocks acquisition and re-acquisition of intravenous morphine self-administration in rats. Pharmacology, Biochemistry and Behavior. (2009) 92(4): 676-682.
[2] Kotagale, Nandkishor Ramdas; Shirbhate, Saurabh Haridas; Shukla, Pradeep; Ugale, Rajesh Ramesh. Agmatine attenuates neuropathic pain in sciatic nerve ligated rats: Modulation by hippocampal sigma receptors. European Journal of Pharmacology. (2013) 714(1-3): 424-431.
[3] Kotagale, Nandkishor R.; Taksande, Brijesh G.; Wadhwani, Paresh J.; Palhade, Mahesh W.; Mendhi, Sachin M.; Gawande, Dinesh Y.; Hadole, Pravin N.; Chopde, Chandrabhan T. Psychopharmacological study of agmatine in behavioral tests of schizophrenia in rodents. Pharmacology, Biochemistry and Behavior. (2012) 100(3): 398-403.
[4] Golding, Bernard T.; Griffin, Roger J.; Mitchinson, Andrew; O'Sullivan, Mary C.New Routes to polyamine analogs Biochemical Society Transactions (1994), 22(4), 391S.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


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RELATED PRODUCTS
X3130Agmatine dihydrochloride
P087Agmatine sulfate

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