P695 Biperiden - AK Scientific
 
 
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  Catalog ID # P695
Biperiden
, 98%
 



IDENTITY
CAS Registry #:[514-65-8]
MDL Number:MFCD05662335
MF:C21H29NO
MW:311.46
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:Off white to cream powder
Melting Point:234-246°C
Shipping:Normal Temperature

BIOLOGICAL INFO
Application(s):Antiparkinsonian agent of the anticholinergic type

REVIEW

 Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of action of centrally active anticholinergic drugs such as biperiden is considered to relate to competitive antagonism of acetylcholine at cholinergic receptors in the corpus striatum, which then restores the balance.

REFERENCES
[1]Nishiyama K, Mizuno T, Sakuta M, Kurisaki H: Chronic dementia in Parkinson's disease treated by anticholinergic agents. Neuropsychological and neuroradiological examination. Adv Neurol. 1993;60:479-83.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


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CATEGORIES

 APIs and Bioactives > AChR Antagonists

USEFUL LINKS

  PubChem