189028-93-1 (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone AKSci V0098
 
 
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  V0098    AKSci Bulk Reagent
(4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone, 98%
 



IDENTITY
CAS Number:189028-93-1
MDL Number:MFCD08061377
MF:C20H18FNO4
MW:355.36
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:88-92°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Other solvents(Soluble): Acetone

REVIEW
 (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone is a key advanced intermediate used in the preparation of ezetimibe.

REFERENCES
[1]Thiruvengadam, Tiruvettipuram K.; Fu, Xiaoyong; Tann, Chou-Hong; McAllister, Timothy L.; Chiu, John S.; Colon, Cesar Process for the synthesis of azetidinones and intermediates for use as hypocholesterolemics PCT Int. Appl. (2000), WO 2000034240 A1 20000615.
[2] Thiruvengadam, Tiruvettipuram K.; Fu, Xiaoyong; Tann, Chou-hong; McAllister, Timothy L.; Chiu, John S.; Colon, Cesar Process for the synthesis of azetidinones U.S. (2001), US 6207822 B1 20010327.
[3] Thiruvengadam, Tiruvettipuram K.; Chiu, John S.; Fu, Xiaoyong; McAllister, Timothy L. Process for the synthesis of azetidinones U.S. Pat. Appl. Publ. (2006), US 20060135755 A1 20060622.
[4] Barden, Timothy C.; Lee, Peter; Martinez, Eduardo J.; Schairer, Wayne C.; Talley, John J. Processes for production of phenolic 4-biphenylylazetidin-2-ones PCT Int. Appl. (2006), WO 2006122216 A2 20061116.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
None

Precautionary Statements
Notavailable

Current as of April 18, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > Hypercholesterolemia


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