70775-75-6 Octenidine dihydrochloride AKSci X4026
 
 
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  X4026    AKSci Bulk Reagent
Octenidine dihydrochloride, 98%
 
N,N'-[Decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene]bis(octylammonium) dichloride
IDENTITY
CAS Number:70775-75-6
MDL Number:MFCD01938808
MF:C36H64Cl2N4
MW:623.83
EINECS:274-861-8
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:208-217°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Octenidine dihydrochloride is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative used in concentrations of 0.1-2.0% for skin, mucous membrane and wound antisepsis. It is similar in its action to quaternary ammonium compounds, but is of somewhat broader spectrum of activity. Octenidine is currently increasingly used in continental Europe as a substitute for quats or chlorhexidine in water- or alcohol-based skin, mucosa and wound antiseptics. In aqueous formulations, it is often potentiated with addition of 2-phenoxyethanol.

REFERENCES
[1]Bailey, Denis M.; DeGrazia, C. George; Hoff, Stephanie J.; Schulenberg, Patsy L.; O'Connor, John R.; Paris, Donald A.; Slee, Andrew McKenzie Bispyridinamines: a new class of topical antimicrobial agents as inhibitors of dental plaque Journal of Medicinal Chemistry (1984), 27(11), 1457-64.
[2] Beilfuss, Wolfgang; Gradtke, Ralf; Streek, Michael Process for the preparation of bis(4-amino-1-pyridinium)alkane salts Eur. Pat. Appl. (2001), EP 1123927 A1 20010816.
[3] Krishna BV, Gibb AP. Use of octenidine dihydrochloride in meticillin-resistant Staphylococcus aureus decolonisation regimens: a literature review. J Hosp Infect. 2010 Mar;74(3):199-203.
[4] Hübner NO, Siebert J, Kramer A.Octenidine dihydrochloride, a modern antiseptic for skin, mucous membranes and wounds.Skin Pharmacol Physiol. 2010;23(5):244-58.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H302+H312; H302+H312+H332; H302+H332; H315; H319; H335

Precautionary Statements
P270; P280; P261; P271; P302+P352; P332+P313; P362; P305+P351+P338; P337+P313; P301+P310+P330; P301+P312+P330; P301+P330+P331; P330; P403+P233; P405; P503; P501

RELATED PRODUCTS
K205Octenidine
X4026Octenidine dihydrochloride

Current as of April 18, 2024


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⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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CATEGORIES
 APIs and Bioactives > Antiseptics
 Specialty Chemicals > Surfactants
 Specialty Chemicals > Surfactants


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