362-07-2 2-Methoxyestradiol AKSci X5011
 
 
Loading Please Wait...
  X5011    AKSci Reference Standard
2-Methoxyestradiol, 98% (HPLC)
 
3,17β-Dihydroxy-2-methoxy-1,3,5(10)-estratriene, 2,3,17β-Trihydroxy-1,3,5(10)-estratriene 2-methyl ether, 1,3,5(10)-Estratriene-2,3,17-triol 2-methyl ether, 2-Hydroxyestradiol 2-methyl ether
IDENTITY
CAS Number:362-07-2
MDL Number:MFCD00010489
MF:C19H26O3
MW:302.41
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:186-190°C
Optical Rotation:+104° (c=55mg/10ml of CHCL3)
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply to certain package sizes. Please check pricing table for an indicator of applicable hazmat fees.

BIOLOGICAL INFO
Solubility:DMSO: 10 mg/mL; ethanol: 10 mg/mL; H2O: insoluble
Application(s):Tubulin polymerization inhibitor
Form:Free Base
Research Area:pulmonary hypertension

REVIEW
 2-Methoxyestradiol (2-ME) is a potent inhibitor of endothelial cell proliferation and angiogenesis. A major estradiol metabolite, it has little affinity for classical estrogen receptors.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H301+H311+H331; H315; H319; H335; H350; H360; H372; H410

Precautionary Statements
P201; P202; P260; P264; P270; P271; P273; P280; P301+P310; P302+P352; P304+P340; P305+P351+P338; P308+P313; P322; P330; P332+P313; P337+P313; P361; P391; P403+P233; P405; P501

Current as of April 23, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives >


PubChem