REVIEW Quinestrol is the 3-cyclopentyl ether of ethinyl estradiol. It is used in hormone replacement therapy, treating symptoms of menopause such as hot flashes. Quinestrol is also used to treat breast and prostate cancer. After gastrointestinal absorption, Quinestrol is stored in adipose tissue where it is slowly released and metabolized principally to the parent compound, ethinyl estradiol.
REFERENCES
[1]
Giannina T, Steinetz BG, Meli A. General biology of quinestrol. Int J Fertil. (1967) Apr-Jun;12(2): 142-7.
[2]
Roland M, Clyman MJ, Decker A, Ober WB, Bronstein SB. Evaluation of estrogen properties of quinestrol in human females. Int J Fertil. (1967) Apr-Jun;12(2): 176-80.
[3]
Donde UM, Virkar KD. Biochemical studies with once-a-month contraceptive pill containing quinestrol-quingestanol acetate. Contraception. (1975) Jun;11(6): 681-8.
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