371242-69-2 IC87114 AKSci SYN1045
 
 
Loading Please Wait...
  SYN1045    
IC87114, >95%
 



IDENTITY
CAS Number:371242-69-2
MDL Number:MFCD09970845
MF:C22H19N7O
MW:397.43
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95%
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 0.66mg/mL, Ethanol <1mg/mL
Application(s):PI3K

REVIEW
 IC87114 is a potent, ATP-competitive, and selective inhibitor of PI3Kdelta. IC50 values (130-500nM) for IC87114 are sub-micromolar over a wide range of ATP concentrations from 10uM to 200uM. IC87114 can selectively inhibit cellular migration but not adhesion as well as cellular polarization. More recent work has shown the PIK3delta inhibition also plays a role in autoimmune disease suppression.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 18, 2024


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.