107133-36-8 Perindopril erbumine AKSci V2111
 
 
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  V2111    
Perindopril erbumine, 98%
 
Perindopril
Perindopril tert-butylamine
IDENTITY
CAS Number:107133-36-8
MDL Number:MFCD02313824
MF:C23H43N3O5
MW:441.60
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:126-130°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: >10 mg/mL, H2O: 10mg/mL
Application(s):Non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor; Antihypertensive Agent
Form:t-Butylamine

REVIEW
 Perindopril is a long-acting ACE inhibitor that is used to treat high blood pressure, heart failure or stable coronary artery disease.

REFERENCES
[1]Hurst M, Jarvis B: Perindopril: an updated review of its use in hypertension. Drugs. 2001;61(6):867-96.
[2] Jastrzebskal M, Widecka K, Naruszewicz M, Ciechanowicz A, Janczak-Bazan A, Foltynska A, Goracy I, Chetstowski K, Wesotowska T: Effects of perindopril treatment on hemostatic function in patients with essential hypertension in relation to angiotensin converting enzyme (ACE) and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms. Nutr Metab Cardiovasc Dis. 2004 Oct;14(5):259-69.
[3] Parker E, Aarons L, Rowland M, Resplandy G: The pharmacokinetics of perindoprilat in normal volunteers and patients: influence of age and disease state. Eur J Pharm Sci. 2005 Sep;26(1):104-13.
[4] Simpson D, Noble S, Goa KL: Perindopril: in congestive heart failure. Drugs. 2002;62(9):1367-77; discussion 1378-9.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
V2111Perindopril erbumine
I553Perindopril

Current as of April 23, 2024


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CATEGORIES
 APIs and Bioactives > ACE Inhibitors


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