162401-32-3 Roflumilast AKSci X4421
 
 
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  X4421    
Roflumilast, 98% (HPLC)
 
3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide, 3-Cyclopropylmethoxy-4-difluoromethoxy-N-[3,5-dichloropyrid-4-yl]-benzamide
IDENTITY
CAS Number:162401-32-3
MDL Number:MFCD00938270
MF:C17H14Cl2F2N2O3
MW:403.21
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:160-162°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 A highly potent, orally active, and selective phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 0.8 nM. Roflumilast has anti-inflammatory properties and is used clinically to treat COPD.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
X4421Roflumilast
X31873-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde
X31883-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid

Current as of April 16, 2024


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