Soluble in DMSO (1 mg/mL), 1:2 DMSO:PBS (pH 7.2) (~0.3 mg/mL), and DMF (~10 mg/mL)
Application(s):
A potent inhibitor of phosphatidylinositol phosphate kinase PIKfyve
Form:
FREE BASE
Research Area:
CANCER
REVIEW YM201636 is a potent inhibitor of phosphatidylinositol phosphate kinase PIP5KIII (PIKfyve). PIKfyve has been noted to synthesize phosphatidylinositol 3,5-bisphosphate and is also reported to be involved in sorting endosomal transport. YM201636 displays the ability to inhibit basal and insulin-activated 2-deoxyglucose uptake and has also been shown to completely block insulin-dependent activation of class IA PI 3-kinase.
All products are stocked and shipped from San Francisco Bay Area, California, USA.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.