125-33-7 Primidone AKSci J10534
 
 
Loading Please Wait...
  J10534    AKSci Reference Standard
Primidone, 99% (HPLC)
 
2-Deoxyphenobarbital
5-Ethyl-5-phenylhexahydropyrimidine-4,6-dione
Mysoline
more..
IDENTITY
CAS Number:125-33-7
MDL Number:MFCD00038662
MF:C12H14N2O2
MW:218.25
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:281-282°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 44mg/mL; H2O: <1mg/mL; EtOH: 3mg/mL
Application(s):GABA receptor agonist
Form:Free Base

REVIEW
 Primidone is a GABA receptor agonist. The mechanism of Primidone's antiepileptic action is not known.

REFERENCES
[1]Williams, Denis (1 August 1956). Treatment of Epilepsy with Mysoline. Proceedings of the Royal Society of Medicine 49 (8): 589-91. PMC 1889099. PMID 13359420.
[2] Morley, D.; N. A. Wynne (January 12, 1957). Acute Primidone Poisoning in a Child. British Medical Journal 1 (5010): 90. doi:10.1136/bmj.1.5010.90. PMC 1974075. PMID 13383203.
[3] Dotevall, Gerhard; Birger Herner (August 24, 1957). Treatment of Acute Primidone Poisoning with Bemegride and Amiphenazole. British Medical Journal 2 (5042): 451-2. doi:10.1136/bmj.2.5042.451. PMC 1961943. PMID 13446511.
[4] van Heijst, A. N.; W. de Jong, R. Seldenrijk, A. van Dijk (June 1983). Coma and crystalluria: a massive primidone intoxication treated with haemoperfusion. Journal of Toxicology. Clinical Toxicology 20 (4): 307-18. doi:10.3109/15563658308990598. PMID 6655772.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H351

Precautionary Statements
P201; P202; P264; P270; P281; P301+P312; P308+P313; P330; P405; P501

Current as of May 10, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
⚠️

WARNING: Attention California residents: This product can expose you to chemicals including Primidone, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.




CATEGORIES
 APIs and Bioactives > Anticonvulsants


PubChem