120011-70-3 Donepezil HCl AKSci J10827
 
 
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  J10827    
Donepezil HCl
, 99% (HPLC), powder
 
2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanone hydrochloride
Aricept




IDENTITY
CAS Number:120011-70-3
MDL Number:MFCD00881312
MF:C24H30ClNO3
MW:415.95
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:223-227°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 1mg/mL; H2O: 31mg/mL; EtOH: 2mg/mL
Application(s):AChE inhibitor; bAChE; hAChE
Form:HCl salt

REVIEW

 A centrally acting reversible acetylcholinesterase inhibitor. The main therapeutic use is in the palliative treatment of mild to moderate Alzheimer's disease.

REFERENCES
[1]Myhrer T, Enger S, Aas P (2010). Behavioral side effects in rats treated with acetylcholinesterase inhibitors suggested used as prophylactics against nerve agents. Pharmacol Biochem Behav. 95(3):338-43. PMID 20184916.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


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Current as of May 10, 2024


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⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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CATEGORIES

 APIs and Bioactives > AChR Agonists, Alzheimer's


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