93479-97-1 Glimepiride AKSci J10973
 
 
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  J10973    
Glimepiride
, 99% (HPLC)
 
Amaryl
Glista OD




IDENTITY
CAS Number:93479-97-1
MDL Number:MFCD00878417
MF:C24H34N4O5S
MW:490.62
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:209-215°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: >10mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):DPP-4 inhibitor
Form:Free Base

REVIEW

 Glimepiride is used to treat type 2 diabetes mellitus. Its mode of action is to increase insulin production by the pancreas. It is not used for type 1 diabetes because the pancreas is no longer able to produce insulin.

REFERENCES
[1]Srivastava S, Saxena GN, Keshwani P, Gupta R (2012). Comparing the efficacy and safety profile of sitagliptin versus glimepiride in patients of type 2 diabetes mellitus inadequately controlled with metformin alone. J Assoc Physicians India. 60:27-30. PMID 22799111.
[2] Gallwitz B, Rosenstock J, Rauch T, Bhattacharya S, Patel S, von Eynatten M, Dugi KA, Woerle HJ (2012). 2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial. Lancet. 380(9840):475-83. PMID 22748821.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of May 9, 2024


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CATEGORIES

 APIs and Bioactives > Diabetes


PubChem