REVIEW Deflazacort is a synthetic glucocorticoid used as an anti-inflammatory and immunosuppressant. It is an inactive prodrug which is metabolized rapidly to the active drug 21-desacetyldeflazacort. Deflazacort has fewer adverse effects on glucose and calcium metabolism and fewer deleterious effects on the neuronal population. Use of deflazacort has been explored largely in patients with Duchenne''s muscular dystrophy.
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