82034-46-6 Loteprednol etabonate AKSci K462
 
 
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  K462    
Loteprednol etabonate, 98% (HPLC)
 



IDENTITY
CAS Number:82034-46-6
MDL Number:MFCD00870765
MF:C24H31ClO7
MW:466.95
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:233-237°C
Optical Rotation:+38.0 to +42.0° (C=1, dioxane)
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 93mg/mL; H2O: <1mg/mL; EtOH: 4mg/mL
Application(s):Glucocorticoid and mineralcorticoid receptors agonist
Form:Free Base

REVIEW
 A corticosteroid used in optometry and ophthalmology for treatment of inflammation of the eye due to allergies, chronic forms of keratitis, vernal keratoconjunctivitis, pingueculitis, and episcleritis.

REFERENCES
[1]Lu E, Fujimoto LT, Vejabul PA, Jew RL (2011). Steroid-induced ocular hypertension with loteprednol etabonate 0.2%--a case report. Optometry. 82(7):413-20. PMID 21543264.
[2] Wu WM, Bodor ET, Howes J, Bodor N (2012). The effects of delta1-cortienic acid on skin blanching, pharmacokinetics and stability of loteprednol etabonate. Pharmazie. 67(5):406-10. PMID 22764572.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of May 10, 2024


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⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Steroid Hormones


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