66898-62-2 Talniflumate AKSci M935
 
 
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  M935    AKSci Bulk Reagent
Talniflumate, 98% (HPLC)
 
Lomucin
Somalgen
Talniflumatum
more..
IDENTITY
CAS Number:66898-62-2
MDL Number:MFCD00866135
MF:C21H13F3N2O4
MW:414.33
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:165-170°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 5 mg/mL clear (warmed)
Application(s):An inhibitor of Cox and Cl-/HCO3- exchange

REVIEW
 Talniflumate is an orally available, potent and selective inhibitor of core mucin-synthesizing enzyme GCNT3 (core 2 b-1,6 N-acetylglucosaminyltransferase). Talniflumate decreases GCNT3 expression and production of mucins in vivo and in vitro. Talniflumate improves responsiveness of pancreatic tumors to gefitinib. Talniflumate is a potent calcium-activated chloride channel (CaCC) blocker.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
None

Precautionary Statements
Notavailable

Current as of May 10, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > NSAIDs


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