24356-94-3 Algestone acetophenide AKSci E483
 
 
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  E483    
Algestone acetophenide, 98% (HPLC)
 
Deladroxone
Bovitrol
Droxone
more..
IDENTITY
CAS Number:24356-94-3
MDL Number:MFCD00056835
MF:C29H36O4
MW:448.59
EINECS:246-195-8
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:146-153°C
Optical Rotation:+49.0° - +53.0° (c=1, CHCl3)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Algestone acetophenide is a synthetic progesterone that has been used in estrus synchronization and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also used therapeutically as a topical anti-inflammatory and is applied topically in the treatment of acne.

REFERENCES
[1]Recio R; Garza-Flores J; Schiavon R; Reyes A; Diaz-Sanchez V; Valles V; Luz de la Cruz D; Oropeza G; Perez-Palacios G. Pharmacodynamic assessment of dihydroxyprogesterone acetophenide plus estradiol enanthate as a monthly injectable contraceptive. Contraception. (1986) 33(6): 579-89.
[2] Kym, Philip R.; Carlson, Kathryn E.; Katzenellenbogen, John A. Progestin 16alpha,17alpha-dioxolane ketals as molecular probes for the progesterone receptor: synthesis, binding affinity, and photochemical evaluation. Journal of Medicinal Chemistry. (1993) 36(9): 1111-19.
[3] Jarquin Gonzalez J D; Elda de Aguirre L; Rodriguez C; Abrego de Aguilar M; Carrillo F; Leon D A; Lima M; Trigueros S; Acosta R. Dihydroxyprogesterone acetophenide 150 mg + estradiol enantate 10 mg as monthly injectable contraceptives Advances in contraception. The Official Journal of the Society for the Advancement of Contraception. (1996) 12(3): 213-25.
[4] Felton H T; Hoelscher E W; Swartz D P Evaluation of use of an injectable progestin-estrogen for contraception Fertility and sterility (1965), 16(5), 665-75.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 30, 2024


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CATEGORIES
 APIs and Bioactives > Steroid Hormones


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