54-31-9 Furosemide AKSci J10011
 
 
Loading Please Wait...
  J10011    
Furosemide
, 99% (HPLC), powder
 
4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoic acid
Frusemide
more..




IDENTITY
CAS Number:54-31-9
MDL Number:MFCD00010549
MF:C12H11ClN2O5S
MW:330.74
EINECS:200-203-6
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:218-220°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 66mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):Sodium Potassium Chloride Symporter Inhibitor
Form:Free Base

REVIEW

 A loop diuretic used in the treatment of congestive heart failure and edema. Furosemide acts by inhibiting NKCC2, the luminal Na-K-2Cl symporter in the thick ascending limb of the loop of Henle.

REFERENCES
[1]Hochman DW (2012). The extracellular space and epileptic activity in the adult brain: explaining the antiepileptic effects of furosemide and bumetanide. Epilepsia. 53 Suppl 1:18-25. PMID 22612805.
[2] Sigmund EE, Vivier PH, Sui D, Lamparello NA, Tantillo K, Mikheev A, Rusinek H, Babb JS, Storey P, Lee VS, Chandarana H (2012). Intravoxel incoherent motion and diffusion-tensor imaging in renal tissue under hydration and furosemide flow challenges. Radiology. 263(3):758-69. PMID 22523327.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Danger

Hazard Statements
H360

Precautionary Statements
P201; P202; P281; P308+P313; P405; P501


Current as of April 26, 2024


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Diuretics


PubChem