137-58-6 Lidocaine AKSci J10173
 
 
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  J10173    
Lidocaine, >99% (GC), powder
 
Alphacaine
Xylocaine
Lignocaine
more..
IDENTITY
CAS Number:137-58-6
MDL Number:MFCD00026733
MF:C14H22N2O
MW:234.34
EINECS:205-302-8
BRN:2215784
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>99% (GC), powder
Physical Form (at 20°C):Solid
Melting Point:66-70°C
Boiling Point:180-182°C (4mmHg)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 47mg/mL; H2O: 9mg/mL; EtOH: 47mg/mL
Application(s):Histamine H1-receptor agonist; Sodium Channel blocker
Form:Free Base

REVIEW
 A common local anesthetic and antiarrhythmic drug. Lidocaine is a selective inverse peripheral histamine H1-receptor agonist.

REFERENCES
[1]Nickel JC, Jain P, Shore N, Anderson J, Giesing D, Lee H, Kim G, Daniel K, White S, Larrivee-Elkins C, Lekstrom-Himes J, Cima M (2012). Continuous intravesical lidocaine treatment for interstitial cystitis/bladder pain syndrome: safety and efficacy of a new drug delivery device. Sci Transl Med. 4(143):143ra100. PMID 22814850.
[2] Benlier E, Eskiocak S, Puyan FO, Sikar EY, Kandulu H, Omurlu IK, Top H, Aygit AC (2012). Effect of lidocaine on reducing injury in a rat electrical burn model. Ann Plast Surg. 69(2):152-6. PMID 22772068.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501

RELATED PRODUCTS
M620Lidocaine
C903Lidocaine hydrochloride monohydrate

Current as of April 30, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > Anaesthetics, Arrhythmia


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