112665-43-7 Seratrodast AKSci J10468
 
 
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  J10468    AKSci Reference Standard
Seratrodast, >98% (HPLC)
 



IDENTITY
CAS Number:112665-43-7
MDL Number:MFCD00875701
MF:C22H26O4
MW:354.44
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:129-131°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Soluble in DMSO (12 mg/ml), ethanol (10 mg/ml), methanol, and NaOH
Application(s):A potent and selective thromboxane A2 receptor (TP) antagonist

REVIEW
 Seratrodast, also known as AA-2414, is a potent and selective antagonist of the TXA2R (thromboxane A2 receptor). Seratrodast is described to produce antioxidant effects, and is demonstrated to inhibit peroxide-induced vasoconstriction in human placenta. Additionally, it inhibit bronchoconstriction in guinea pigs in response to leukotriene D4, U-46619, and platelet activating factor.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 30, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Asthma


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