89-57-6 Mesalamine AKSci J10791
 
 
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  J10791    
Mesalamine, 99% (HPLC), powder
 
5-Aminosalicylic acid
IDENTITY
CAS Number:89-57-6
MDL Number:MFCD00007877
MF:C7H7NO3
MW:153.14
EINECS:201-919-1
BRN:2090421
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:275-282°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 31mg/mL; H2O: <1mg/mL; EtOH: 31mg/mL
Application(s):Cyclooxygenase Inhibitor
Form:Free Base

REVIEW
 An anti-inflammatory drug used to treat inflammatory bowel disease, such as ulcerative colitis and mild-to-moderate Crohn's disease.

REFERENCES
[1]Gao X, Zhang FB, Ding L, Liu H, Wang XD, Chen BL, Bi HC, Xiao YL, Zhao LZ, Chen MH, Huang M, Hu PJ (2012). The potential influence of 5-aminosalicylic acid on the induction of myelotoxicity during thiopurine therapy in inflammatory bowel disease patients. Eur J Gastroenterol Hepatol. 24(8):958-64. PMID 22664938.
[2] Nguyen GC, Gulamhusein A, Bernstein CN (2012). 5-aminosalicylic acid is not protective against colorectal cancer in inflammatory bowel disease: a meta-analysis of non-referral populations. Am J Gastroenterol. 107(9):1298-304; quiz 1297, 1305. PMID 22751467.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 30, 2024


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All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > GI Diseases
 Aryl and Aliphatic Building Blocks > Carboxylic Acids, Amines, Alcohols
 Aryl and Aliphatic Building Blocks > Carboxylic Acids, Amines, Alcohols


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