A hazmat fee may apply to certain package sizes. Please check pricing table for an indicator of applicable hazmat fees.
REVIEW Tetracaine also known as amethocaine (trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. It can be applied as a cream or as a patcvh, plaster or peel. In regard to its mode of action, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
REFERENCES
[1]
WIEDLING S; TEGNER C LOCAL ANESTHETICS Progress in medicinal chemistry (1963), 19, 332-98.
[2]
Covino B G Comparative clinical pharmacology of local anesthetic agents Anesthesiology (1971), 35(2), 158-67.
[3]
Webb, Alistair I.; Pablo, Luisito S. Edited by Riviere, Jim Edmond; Papich, Mark G Local Anesthetics Veterinary Pharmacology and Therapeutics (9th Edition) (2009), 381-399.
All products are stocked and shipped from San Francisco Bay Area, California, USA.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
Add to Favorites 
Delete from Favorites 
