1508-75-4 Tropicamide AKSci J10912
 
 
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  J10912    AKSci Reference Standard
Tropicamide, 99% (HPLC)
 
N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide
IDENTITY
CAS Number:1508-75-4
MDL Number:MFCD00058580
MF:C17H20N2O2
MW:284.35
EINECS:216-140-2
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:96-97°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Anticholinergic and a muscarinic receptor subtype M4-preferring antagonist

REVIEW
 Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle.

REFERENCES
[1]Manny RE, Hussein M, Scheiman M, Kurtz D, Niemann K, Zinzer K (July 2001). Tropicamide (1%): an effective cycloplegic agent for myopic children. Investigative Ophthalmology & Visual Science 42 (8): 1728-35. PMID 11431435.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302+H312+H332; H315; H317; H319; H335

Precautionary Statements
P261; P264; P270; P271; P272; P280; P301+P312; P302+P352; P304+P340; P305+P351+P338; P312; P322; P330; P333+P313; P337+P313; P362; P403+P233; P405; P501

Current as of May 14, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Ophthalmology, AChR Antagonists


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