May darken in storage, particularly when exposed to light and elevated temperatures.
DOT/IATA TRANSPORT INFORMATION
Not hazardous material
BIOLOGICAL INFO
Solubility:
CH2CL2: 25mg/ml
REVIEW Sesamol is a natural organic compound which is a component of sesame oil. Sesamol has been found to be an antioxidant that may prevent the spoilage of oils, and may protect the body from damage from free radicals. It also may prevent the spoilage of oils by acting as an antifungal. Sesame oil is used in Ayurvedic medicine and sesamol may play a key role in this traditional field. Sesamol possesses a number of pharmacological properties which include anti-inflammatory, antioxidant, and neuroprotective properties. Sesamol pretreatment offers radioprotection and prevents radiation induced chromosomal aberrations in human blood lymphocytes.
REFERENCES
[1]
Joo Yeon Kim, Dong Seong Choi and Mun Yhung Jung Antiphoto-oxidative Activity of Sesamol in Methylene Blue- and Chlorophyll-Sensitized Photo-oxidation of Oil J. Agric. Food Chem., 2003, 51 (11), 3460 -3465.
[2]
Ohsawa, Toshiko. Sesamol and sesaminol as antioxidants.New Food Industry (1991), 33(6), 1-5.
[3]
Wynn, James P.; Kendrick, Andrew; Ratledge, Colin. Sesamol as an inhibitor of growth and lipid metabolism in Mucor circinelloides via its action on malic enzyme. Lipids (1997), 32(6), 605-610.
[4]
Ito N, Hirose M.Antioxidants--carcinogenic and chemopreventive properties. Adv Cancer Res. 1989;53:247-302.
[5]
Hsu DZ, Chen YW, Chu PY, Periasamy S, Liu MY. Protective effect of 3,4-methylenedioxyphenol (sesamol) on stress-related mucosal disease in rats. Biomed Res Int. 2013;2013:481827.
[6]
Thushara RM, Hemshekhar M, Sunitha K, Kumar MS, Naveen S, Kemparaju K, Girish KS. Sesamol induces apoptosis in human platelets via reactive oxygen species-mediated mitochondrial damage. Biochimie. 2013 Nov;95(11):2060-8.
[7]
Nayak PG, Paul P, Bansal P, Kutty NG, Pai KS.Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts. J Pharm Pharmacol. 2013 Jul;65(7):1083-93.
[8]
Kumar N, Mudgal J, Parihar VK, Nayak PG, Kutty NG, Rao CM.Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia. Lipids. 2013 Jun;48(6):633-8.
[9]
Hemshekhar M, Thushara RM, Jnaneshwari S, Devaraja S, Kemparaju K, Girish KS. Attenuation of adjuvant-induced arthritis by dietary sesamol via modulation of inflammatory mediators, extracellular matrix degrading enzymes and antioxidant status. Eur J Nutr. 2013 Oct;52(7):1787-99.
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