552325-73-2 (free base) A-674563 HCl AKSci SYN1110
 
 
Loading Please Wait...
  SYN1110    
A-674563 HCl, >95%
 
A674563
IDENTITY
CAS Number:552325-73-2 (free base)
MDL Number:MFCD18711680
MF:C22H22N4O.HCl
MW:394.9
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95%
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 72 mg/mL, Ethanol <12 mg/mL
Application(s):AKT - PKA - CDK7 - CDK5 - CDK4 - CDK2

REVIEW
 A-674563 is a potent, orally available Akt1 inhibitor with an IC50 of 11 nM. It also displays activity against PKA and CDK2 with IC50 values of 16 and 46 nM respectively.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of May 20, 2024


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.