87848-99-5 Acrivastine AKSci L917
 
 
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  L917    AKSci Reference Standard
Acrivastine
, 98% (HPLC), powder
 
(E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid




IDENTITY
CAS Number:87848-99-5
MDL Number:MFCD00869830
MF:C22H24N2O2
MW:348.44
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:222°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: >2 mg/mL (warmed)
Application(s):Second-generation H1-receptor antagonist antihistamine

REVIEW

 Acrivastine is a short acting second-generation histamine H1-receptor antagonist with a rapid onset of action, used for the treatment of allergies and hay fever.

REFERENCES
[1]Brogden RN, McTavish D.; Acrivastine. A review of its pharmacological properties and therapeutic efficacy in allergic rhinitis, urticaria and related disorders. Drugs. 1991 Jun;41(6):927-40.
[2] Gibson JR, Manna VK, Salisbury J.; Acrivastine: a review of its dermatopharmacology and clinical activity., J Int Med Res. 1989;17 Suppl 2:28B-34B
[3] Bojkowski CJ, Gibbs TG, Hellstern KH, Major EW, Mullinger B.; Acrivastine in allergic rhinitis: a review of clinical experience.J Int Med Res. 1989;17 Suppl 2:54B-68B.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
H413

Precautionary Statements
P273; P501


Current as of April 26, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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⚠️
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CATEGORIES

 APIs and Bioactives > Antihistamines


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