371942-69-7 YM201636 HCl AKSci SYN1094
 
 
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  SYN1094    
YM201636 HCl, >95%
 
YM201636
IDENTITY
CAS Number:371942-69-7
MDL Number:MFCD16038303
MF:C25H21N7O3.HCl
MW:467.48
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95%
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 35mg/mL, Ethanol <1mg/mL
Application(s):PIKfyve

REVIEW
 YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 of 33nM). It disrupts retroviral budding from cells, apparently by interfering with the endosomal sorting complex required for transport (ESCRT) machinery. In adipocytes, YM-201636 also inhibits basal and insulin-activated 2-deoxyglucose uptake (IC50 of 54nM).

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 26, 2024


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