951151-97-6 JNJ-38158471 AKSci SYN1133
 
 
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  SYN1133    
JNJ-38158471, 98%
 
JNJ38158471
IDENTITY
CAS Number:951151-97-6
MDL Number:MFCD22631501
MF:C15H17ClN6O3
MW:364.79
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:15 mM in DMSO
Application(s):VEGFR-2

REVIEW
 JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with an IC50 of 40 nM. It also inhibits closely related tyrosine kinases such as Ret (IC50 of 180 nM) and Kit (C50 of 500 nM). It has no significant activity (>1 uM) against VEGFR-1 and VEGFR-3.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 29, 2024


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All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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