AMT Click Chemistry - AK Scientific
 
 


Structure Search
New Products Weekly

AKSci Categories:
Inhibitors, Bioactives & Reference
Compounds
• Pharmacology
• Research Area
• Natural Product & Supplement
• Biocides
Building Blocks and Intermediates
• Aryl & Aliphatic
• Heterocyclic
• Amino Acids
• Inorganics
• Organoborons
• Screening Compounds
Reagents for Synthesis
• Common Reagents
• Chiral Synthesis
• Organosilicons
• Peptide Coupling
Biochemicals and more
• Carbohydrates
• Nucleobases
• Specialty Chemicals

AMT Products:
• Biaryls    
• Click Chemistry    
• Organoborons     
• Organosilicons    
• Other AMT Compounds    
• Bioactives
• General Compounds
• Halogenated Compounds
• Molecular Fluorophores & Dyes
• PEG Reagents & Linkers
• AMT No CAS # Products
• AMT Literature

HTS-Biochemie Products:
• HTS Screening Compounds

Recently Viewed Items:

No recently viewed items.


 
Loading Please Wait...

Dual-Functional AMT Products for Click Chemistry
Among click chemistry reactions, the Huisgen 1,3-dipolar cycloaddition of azides to alkynes to give 1,2,3-triazoles is, as Dr. Sharpless called it, "the cream of the crop".
AK Scientific stocks unique alkynes and azides AMT, suited both for the Huisgen click reaction and for Suzuki coupling.
AMT Click Chemistry Fact Sheet

Azides
Catalog #
(structure)		 Name
AMTB1241 2-(4-(2-Azidoethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
AMTB503 2-(4-(Azidomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
AMTB513 2-(3-(Azidomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
AMTB514 Potassium 4-(azidomethyl)phenyltrifluoroborate
AMTB515 2-(2-(Azidomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
AMTB521 Potassium 3-(azidomethyl)phenyltrifluoroborate
AMTB525 Potassium 2-(azidomethyl)phenyltrifluoroborate
AMTB531 2-(4-(Azidomethyl)phenyl)-2,3-dihydro-1H-naptho[1,8-de][1,3,2]diazaborinine
AMTB662 Tetrabutylammonium 2-(azidomethyl)phenyl trifluoroborate
AMTB669 Tetrabutylammonium 4-(azidomethyl)phenyl trifluoroborate
AMTB683 2-(4-(1-Azidoethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Alkynes
Catalog #
(structure)		 Name
AMTB136 [4-(Prop-2-ynylamine-1-carbonyl)phenyl]boronic acid pinacol ester
AMTB140 [3-(Prop-2-ynylamine-1-carbonyl)phenyl]boronic acid pinacol ester
AMTB199 4-(Phenylethynyl)benzeneboronic acid pinacol ester
AMTB200 4-[(Trimethylsilyl)ethynyl]benzeneboronic acid pinacol ester
AMTB201 4,4,5,5-Tetramethyl-2-(3-trimethylsilanylethynyl-phenyl)-[1,3,2]dioxaborolane
AMTB202 Bis-(4,4,5,5-Tetramethyl-2-(4-phenyl)-[1,3,2]dioxaborolane)acetylene
AMTB205 2-(4-Ethynyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
AMTB207 4-([4-(Methoxycarbonyl)phenyl]ethynyl)benzeneboronic acid pinacol ester
AMTB208 4-(3-Hydroxy-1-propynyl)benzeneboronic acid pinacol ester
AMTB210 3-Ethynylbenzeneboronic acid pinacol ester
AMTB224 4-(4-Methoxyphenylethynyl)benzeneboronic acid pinacol ester
AMTB225 4-(4-Chlorophenylethynyl)benzeneboronic acid pinacol ester
AMTB466 2-(4-Ethynylphenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine
AMTB499 2-(4-((Trimethylsilyl)ethynyl)phenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine
AMTB512 1,2-Bis(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyne
AMTB864 2-4((4-Methoxyphenyl)ethynl)phenyl)-2.3.dihydro-1H-naphtho[1.8-de][1.3.2]diazaborinine
AMTB870 Potassium 4-((4-Methoxycarbonyl)phenyl)ethynyl)phenyltrifluoroborate

References
  1. Kolb, H. C.; Finn, M. G.; Sharpless, K. B. Click Chemistry: Diverse Chemical Function from a Few Good Reactions. Angew. Chem., Int. Ed. 2001, 40, 2004-2021.
  2. Tron, G. C.; Pirali, T.; Billington, R. A.; Canonico, P. L.; Sorba, G.; Genazzani, A. A. Click Chemistry Reactions in Medicinal Chemistry: Applications of the 1,3-dipolar Cycloaddition between Azides and Alkynes. Med. Res. Rev. 2007, 28, 278-308.
  3. AMTB503: White, J. R.; Price, G. J.; Schiffers, S.; Raithby, P. R.; Plucinski, P. K.; Frost, C. G. A Modular Approach to Catalytic Synthesis Using a Dual-functional Linker for Click and Suzuki Coupling Reactions. Tetrahedron Lett. 2010, 51, 3913-3917.
  4. AMTB515: Mulla, K.; Dongare, P.; Zhou, N.; Chen, G.; Thompson, D. W.; Zhao, Y. Highly Sensitive Detection of Saccharides under Physiological Conditions with Click Synthesized Boronic Acid-Oligmer Fluorophores. Org. Biomol. Chem. 2011, 9, 1332-1336.
  5. AMTB514: Molander, G. A.; Ham, J. Synthesis of Functionalized Organotrifluoroborates via the 1,3-Dipolar Cycloaddition of Azides. Org. Lett. 2006, 8, 2767-2770.

See AMT's website or contact us for more info about AMT's unique compounds.